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Sanitization The injection site, typically the upper arm, thigh, or buttocks, will be cleaned and sanitized to prevent any risk of infection

The magnitude of the NAD + -elevation effect of NNMT inhibition in vivo, and its contribution to the metabolic phenotype relative to the methylation effects, remains an active area of research

Do not freeze the medicine

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Following the transfer of aminopropyl groups, dcSAM transforms into 5-deoxy-5-methylthioadenosine, which then can undergo a series of steps in the Met salvage pathway to regenerate adenine and Met (Lauinger and Kaiser, 2021)